Soluble P-selectin is the smoke, not the fire
نویسندگان
چکیده
منابع مشابه
Soluble P-selectin is the smoke, not the fire.
intermediary drives ibrutinib resistance, whereas presence of a complex karyotype and Del17p are predictive of progression while on ibrutinib. Additional work in larger cohorts of samples may be required to address whether USP7 inhibition would be sufficient to target disease in this subgroup of patients. In conclusion, despite unresolved queries, this study identifies that USP7 is an attractiv...
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BACKGROUND P-selectin, a cell-surface adhesion molecule involved in leukocyte rolling and attachment, has been hypothesized to play a role in the initiation of atherosclerosis. However, little clinical data are available evaluating the role of soluble P-selectin in determining vascular risk. METHODS AND RESULTS In a large-scale prospective study of apparently healthy women, we measured baseli...
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The ankle-brachial index (ABI), a ratio of systolic blood pressure measured at the ankle and the brachial artery, is a simple noninvasive screening test used to diagnose peripheral arterial disease (PAD). PAD affects over 12 million people in the United States and its prevalence increases with increasing age (1,2). Patients with an abnormal ABI, defined as 0.90 or 1.40, are at increased risk of...
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ژورنال
عنوان ژورنال: Blood
سال: 2017
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2017-05-786319